Espíritu Santo River Nature Reserve
Visit Espíritu Santo River Nature Reserve
Tours & day trips
See all 133 activities
El Yunque Rainforest Waterslide, Rope Swing & Cliff Jumps
Activity duration is 3 hours
9.6 out of 10 with 507 reviews
Free cancellation available
Private & custom tours
See all 28 activities
Puerto Rico Can Am UTV Adventure and Sightseeing Tour
Activity duration is 1 hour
8.4 out of 10 with 108 reviews
Free cancellation available
Wildlife & nature
See all 14 activities
From Carolina: Horse Riding at a Private Ranch
Activity duration is 2 hours
9.2 out of 10 with 165 reviews
Free cancellation available
Food, drink & nightlife
See all 12 activities
Fajardo: Bioluminescent Lagoon Kayak or Full Moon Kayak Tour
Activity duration is 3 hours
9.6 out of 10 with 76 reviews
Free cancellation available
Winter activities
See all 5 activities
Luquillo: Guided Jet Ski Tour of Luquillo Beach
Activity duration is 30 minutes
8.4 out of 10 with 68 reviews
Free cancellation available
Stay near popular Espíritu Santo River Nature Reserve attractions
Top Espíritu Santo River Nature Reserve Hotel Deals
Check availability on hotels close to Espíritu Santo River Nature Reserve

Hyatt Regency Grand Reserve Puerto Rico
200 Coco Beach Blvd. Highway 955-I Río Grande

Four Seasons Resort and Residences Puerto Rico
State Road 187 Kilometer 4.2 Río Grande

The Country Club Residences at Grand Reserve
200 Coco Beach Boulevard Río Grande PR

Grand Bay by Otium
KM 7 Grand Bay Beach Club Carr. 187 Río Grande

Wyndham Grand Rio Mar Rainforest Beach and Golf Resort
6000 Rio Mar Boulevard Río Grande

Picuas Village
14 Camino las Picüas Río Grande Río Grande

Aquatika Paraiso Tropical
PR-187 9.2 km Loiza PR

The Sandpit by Lepute
PR-965, Lote 8 Loíza
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.






























