10 Best Business Hotels in Eastern South Dakota for 2026

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Our top choices for Eastern South Dakota business-friendly hotels

Desk, laptop workspace, blackout curtains, soundproofing

1. AeroStay Hotel

North Sioux Falls

Steve

RM610

RM699 total

includes taxes & fees

16 Aug - 17 Aug

Desk, laptop workspace, soundproofing, iron/ironing board

2. Comfort Inn & Suites at Sanford Sports Complex

Northwest Sioux Falls

Patricia

RM437

RM488 total

includes taxes & fees

30 Aug - 31 Aug

Desk, blackout curtains, iron/ironing board, free cots/infant beds

3. Clarion Pointe Sioux Falls Airport

Northwest Sioux Falls

Joseph

RM392

RM439 total

includes taxes & fees

23 Aug - 24 Aug

Premium bedding, desk, iron/ironing board, free WiFi

4. Grandstay Hotel And Suites Luverne

Luverne

Scott

RM475

RM522 total

includes taxes & fees

12 Aug - 13 Aug

Premium bedding, desk, laptop workspace, blackout curtains

5. AmericInn by Wyndham Hartford SD

Hartford

Bryant

RM414

RM450 total

includes taxes & fees

23 Aug - 24 Aug

6. Holiday Inn Express & Suites Sioux City North-Event Center by IHG

Dakota Dunes

Kristina

RM450

RM483 total

includes taxes & fees

23 Aug - 24 Aug

7. De Smet Super Deluxe Inn and Suites

De Smet

Edward

RM390

RM424 total

includes taxes & fees

15 Aug - 16 Aug

Desk, laptop workspace, blackout curtains, free WiFi

8. Econo Lodge Watertown

Watertown

Gary

RM249

RM279 total

includes taxes & fees

16 Aug - 17 Aug

View all properties

Top Eastern South Dakota Hotel Reviews

Thunderbird Lodge

10/10 Excellent

"Always a fine location never had any problems"

Clarion Pointe Sioux Falls Airport

10/10 Excellent

"Booked at the last minute, everything was great . Hotel was very clean . We loved it"

AeroStay Hotel

10/10 Excellent

"The room was immaculate. I was able to get something to eat for breakfast at 3 am before my 5 am flight. The staff was amazing and very helpful. When I asked how to adjust my room temperature, she told me and then set it to the requested temperature while I went to return my rental car. The convenience is unparalleled."

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

10/10 Excellent

"We were a little nervous because of some of the negative reviews, but we were very pleased with the location. It's not a 5-star resort, but for an overnight stay with young kids, it was perfect on our long road trip. The perfect midway for our 13-hour drive. The waterpark was a perfect option for the kids to get out, swim, and have some fun. The Pizza joint was great! The reviews that were complaining about staff or property, I don't agree with. My wife is very picky about places, and she didn't have any issues."

Kelly Inn & Suites Mitchell South Dakota

8/10 Good

"AC was not very strong. Great breakfast and location and decor. Staff was kind and helpful to provide fan for the room."

Days Inn by Wyndham Sioux Falls Airport

10/10 Excellent

"It’s good overall in price we paid"

Frequently asked questions

How much do business-friendly hotels in Eastern South Dakota cost?

Rates for business hotels in Eastern South Dakota range between RM279 and RM699 per night. No matter your budget, Expedia can help you find the ideal space to get your work done. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

What are the best business-friendly hotels in Eastern South Dakota?

There are multiple business-friendly hotels in Eastern South Dakota with a total average guest review rating of 8.9, so you're sure to find a place that suits your needs. Heading to Sioux Falls? Hotel On Phillips is a top choice for corporate travellers. This 2.5-stars option includes amenities such as pillow top mattresses and a Champagne service. Fairfield Inn & Suites Sioux Falls Airport also scores top marks from business guests. Make use of pillow top mattresses and a swimming pool at this 3-stars escape in Sioux Falls.

How many business-friendly hotels are there in Eastern South Dakota?

There are 114 business-friendly hotels in Eastern South Dakota. When work takes you out of town, Expedia makes it easy to find the ideal space with the amenities you want.

What are the best cheap business-friendly hotels in Eastern South Dakota?

That depends on which part of Eastern South Dakota work is taking you. If you're off to Sioux Falls, Hotel On Phillips meets the needs of business travellers at an affordable price. Pillow top mattresses and a cafe are among its many conveniences. On your way to Mitchell? Consider staying at Hampton Inn Mitchell. A swimming pool and designer toiletries help make this cheaper property a top pick for corporate visitors. Business-friendly hotels start at RM279 per night, so that important work trip doesn't have to stretch your finances. Eager to see the sights of Eastern South Dakota without blowing the budget? Take a break from your work events to visit popular free attractions like St. Joseph Cathedral in Sioux Falls. Mitchell also has loads of things to do that don't cost a dime, including Dakota Discovery Museum. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.

Are there any family-friendly hotels in Eastern South Dakota that are also business friendly?

If you're travelling for business in Eastern South Dakota and bringing the family along with you, Expedia will help you locate a cosy and convenient stay. Clubhouse Hotel Suites Sioux Falls in Sioux Falls is an excellent option for those juggling work and leisure. This 3-stars property comes with all the amenities you'll need, like complimentary breakfast and a children's pool. Holiday Inn & Suites Sioux Falls - Airport, an IHG Hotel is another fantastic choice in Sioux Falls. Enjoy the best of both worlds — combine corporate travel and quality time with your family at this 3-stars property. WiFi and laundry facilities are just two of the many conveniences you'll find here. When you've finished work, it's time to explore Sioux Falls with the kids. Popular family-friendly attractions include Great Plains Zoo and Wild Water West.

Why book your business-friendly hotel in Eastern South Dakota with Expedia?

With conveniences like meeting rooms, 24-hour room service and on-site restaurants, our business-friendly properties come with everything you'll need to settle that big contract — and then chill! Enter your preferred dates and travel destination and Expedia will help you with everything else.

How can I find cheap business-friendly hotels in Eastern South Dakota?

When work takes you to Eastern South Dakota, our "business friendly" filter will help you find the perfect hotel. From included breakfast and free WiFi to meeting rooms and workspaces, they come with the amenities you need to get the job done. Another tip? Narrow your search by your budget and preferred star rating to view the most affordable accommodation.

What is there to do in Eastern South Dakota near my business-friendly hotel?

There are so many things to keep you entertained in Eastern South Dakota. If you're off to Sioux Falls, you'll want to check out Great Plains Zoo, Washington Pavilion of Arts and Science and St. Joseph Cathedral. Planning to stay in Mitchell? Dakota Discovery Museum, Corn Palace and Mitchell Aquatic Centre are popular attractions here.

Room 1

Change your mind

Treat yourself

Be picky

Check availability on Eastern South Dakota Business Hotels

Our top choices for Eastern South Dakota business-friendly hotels

1. AeroStay Hotel

2. Comfort Inn & Suites at Sanford Sports Complex

3. Clarion Pointe Sioux Falls Airport

4. Grandstay Hotel And Suites Luverne

5. AmericInn by Wyndham Hartford SD

6. Holiday Inn Express & Suites Sioux City North-Event Center by IHG

7. De Smet Super Deluxe Inn and Suites

8. Econo Lodge Watertown

9. Country Inn & Suites by Radisson, Dakota Dunes, SD

10. Days Inn by Wyndham Watertown

Top Eastern South Dakota Hotel Reviews

Thunderbird Lodge

Clarion Pointe Sioux Falls Airport

AeroStay Hotel

Ramada by Wyndham Sioux Falls Airport-Waterpark & Event Ctr

Kelly Inn & Suites Mitchell South Dakota

Days Inn by Wyndham Sioux Falls Airport

Frequently asked questions

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