Hotels in East Main Street, Grand Junction

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30 Dec - 31 Dec
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31 Dec - 1 Jan
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2 Jan - 4 Jan
Next weekend
9 Jan - 11 Jan

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Our top choices for East Main Street hotels

Free continental breakfast
La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction

La Quinta Inn & Suites by Wyndham Grand Junction
3.0 star property
Horizon Drive District, 5.4 km from East Main Street
8.8 out of 10, Excellent, (2742)
"Easy check in with super friendly staff!!"
United States
Andrew
The price is RM300
RM344 total
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn & Suites by Wyndham Grand Junction
Property entrance
Best Western Grande River Inn & Suites

Best Western Grande River Inn & Suites

Best Western Grande River Inn & Suites
2.5 star property
8.7 km from East Main Street
8.8 out of 10, Excellent, (796)
"Very nice place."
United States
Harold
The price is RM375
RM395 total
includes taxes & fees
5 Jan - 6 Jan 2026
Best Western Grande River Inn & Suites
Reception
Ramada by Wyndham Grand Junction

Ramada by Wyndham Grand Junction

Ramada by Wyndham Grand Junction
2.5 star property
Horizon Drive District, 5.3 km from East Main Street
8.4 out of 10, Very good, (1866)
"Easy check in and clean accommodations "
United States
Mark
The price is RM220
RM253 total
includes taxes & fees
6 Jan - 7 Jan 2026
Ramada by Wyndham Grand Junction
Breakfast served
Grand Vista Hotel

Grand Vista Hotel

Grand Vista Hotel
3.5 star property
Horizon Drive District, 5.5 km from East Main Street
8.2 out of 10, Very good, (3471)
"Second time staying here will be back again next year"
United States
Sue
Grand Vista Hotel
Free daily continental breakfast
Super 8 by Wyndham Grand Junction Colorado

Super 8 by Wyndham Grand Junction Colorado

Super 8 by Wyndham Grand Junction Colorado
2.0 star property
Horizon Drive District, 4.8 km from East Main Street
7.4 out of 10, Good, (1004)
"Great staff"
United States
Theresa
The price is RM207
RM237 total
includes taxes & fees
10 Jan - 11 Jan 2026
Super 8 by Wyndham Grand Junction Colorado
Dinner served
Wine Country Inn Palisade

Wine Country Inn Palisade

Wine Country Inn Palisade
3.5 star property
17.1 km from East Main Street
9.6 out of 10, Exceptional, (1001)
"Great location, excellent accommodations, and staff is very friendly."
United States
Bill
Wine Country Inn Palisade
Restaurant
Tru by Hilton Grand Junction Downtown

Tru by Hilton Grand Junction Downtown

Tru by Hilton Grand Junction Downtown
2.5 star property
Historic Grand Junction, 1.4 km from East Main Street
9.2 out of 10, Wonderful, (1002)
"Good place to stay when you are going on a long trip. Staff was friendly and in a good location of downtown. "
United States
Guru Prasad
The price is RM329
RM378 total
includes taxes & fees
7 Jan - 8 Jan 2026
Tru by Hilton Grand Junction Downtown
Exterior
Spoke and Vine Motel

Spoke and Vine Motel

Spoke and Vine Motel
2.5 star property
17.4 km from East Main Street
9.8 out of 10, Exceptional, (158)
"Spoke and Vine is such a cute motel! The staff was very friendly and the lobby bar area is very cute! They have great beverages on tap and comfortable chairs to sit in. The rooms are small but have everything you need for the stay. And they will even bring breakfast to you in the morning! "
United States
Emily
The price is RM603
RM672 total
includes taxes & fees
31 Dec - 1 Jan 2026
Spoke and Vine Motel
Iron/ironing board, free cots/infant beds, rollaway beds, free WiFi
Econo Lodge Grand Junction North

Econo Lodge Grand Junction North

Econo Lodge Grand Junction North
2.0 star property
Horizon Drive District, 5.2 km from East Main Street
8.4 out of 10, Very good, (1000)
"Hotel was easy to find and worked quite well for a good night sleep after driving 13 hours. "
United States
Peter
The price is RM200
RM230 total
includes taxes & fees
7 Jan - 8 Jan 2026
Econo Lodge Grand Junction North
Living area
Camp Eddy

Camp Eddy

Camp Eddy
1.0 star property
Pear Park, 1.5 km from East Main Street
9.4 out of 10, Exceptional, (295)
"The location was super close to everything and I love the community they're building at Camp Eddy."
United States
Stephanie ML
The price is RM248
RM493 total
includes taxes & fees
4 Jan - 5 Jan 2026
Camp Eddy
Lobby
Quality Inn Grand Junction near University

Quality Inn Grand Junction near University

Quality Inn Grand Junction near University
3.0 star property
Horizon Drive District, 4.9 km from East Main Street
8.6 out of 10, Excellent, (1003)
"Room very clean and pleasant. Staff very friendly and helpful. Complimentary (hot) Breakfast was the best I’ve ever had - anywhere ! Good pricing for the room too! "
United States
Douglas
The price is RM224
RM257 total
includes taxes & fees
5 Jan - 6 Jan 2026
Quality Inn Grand Junction near University
Terrace/patio
Courtyard by Marriott Grand Junction

Courtyard by Marriott Grand Junction

Courtyard by Marriott Grand Junction
3.0 star property
Horizon Drive District, 5.6 km from East Main Street
8.4 out of 10, Very good, (1002)
"Nice staff and ER stay when my flight was delayed overnight. The breakfast options were great too."
United States
Rachel
The price is RM365
RM418 total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott Grand Junction
Billiards
Clarion Inn Grand Junction

Clarion Inn Grand Junction

Clarion Inn Grand Junction
2.5 star property
Horizon Drive District, 5.3 km from East Main Street
8.4 out of 10, Very good, (1701)
"Amazing place ro stay verry accomodateing"
United States
justin
The price is RM292
RM334 total
includes taxes & fees
20 Jan - 21 Jan 2026
Clarion Inn Grand Junction
Exterior
La Quinta Inn & Suites by Wyndham Fruita

La Quinta Inn & Suites by Wyndham Fruita

La Quinta Inn & Suites by Wyndham Fruita
3.0 star property
18.8 km from East Main Street
8.4 out of 10, Very good, (1002)
"Great breakfast and easy to walk to places next door "
United States
Amber
The price is RM287
RM329 total
includes taxes & fees
1 Jan - 2 Jan 2026
La Quinta Inn & Suites by Wyndham Fruita
Lobby
Comfort Inn & Suites Fruita - Grand Junction

Comfort Inn & Suites Fruita - Grand Junction

Comfort Inn & Suites Fruita - Grand Junction
2.5 star property
18.5 km from East Main Street
8.4 out of 10, Very good, (1004)
"The location was convenient and the staff was friendly. "
United States
Charles
The price is RM267
RM305 total
includes taxes & fees
31 Dec - 1 Jan 2026
Comfort Inn & Suites Fruita - Grand Junction
Exterior
Holiday Inn & Suites Grand Junction by IHG

Holiday Inn & Suites Grand Junction by IHG

Holiday Inn & Suites Grand Junction by IHG
3.0 star property
Horizon Drive District, 5.4 km from East Main Street
8.6 out of 10, Excellent, (1001)
"Room was clean, front office staff was nice. "
United States
Patricia
The price is RM360
RM413 total
includes taxes & fees
12 Jan - 13 Jan 2026
Holiday Inn & Suites Grand Junction by IHG
Land view from property
The Homestead

The Homestead

The Homestead
4.5 star property
20.4 km from East Main Street
10.0 out of 10, Exceptional, (63)
"Very beautiful setting in a cute town famed for its Palisade Peaches!"
United States
Ronald
The price is RM724
RM762 total
includes taxes & fees
5 Jan - 6 Jan 2026
The Homestead
Terrace/patio
Doubletree Hotel Grand Junction

Doubletree Hotel Grand Junction

Doubletree Hotel Grand Junction
4.0 star property
Horizon Drive District, 5 km from East Main Street
8.2 out of 10, Very good, (1003)
"Nice looking hotel."
United States
Richard
The price is RM361
RM414 total
includes taxes & fees
6 Jan - 7 Jan 2026
Doubletree Hotel Grand Junction
Exterior
Hampton Inn Grand Junction Downtown/Historic Main Street

Hampton Inn Grand Junction Downtown/Historic Main Street

Hampton Inn Grand Junction Downtown/Historic Main Street
2.5 star property
Historic Grand Junction, 1.5 km from East Main Street
8.8 out of 10, Excellent, (1000)
"Very clean, well managed, and a nice overall stay"
United States
Jeff
The price is RM395
RM453 total
includes taxes & fees
6 Jan - 7 Jan 2026
Hampton Inn Grand Junction Downtown/Historic Main Street
Rooftop terrace
Hotel Maverick

Hotel Maverick

Hotel Maverick
4.0 star property
Capitol Hill, 1.6 km from East Main Street
9.6 out of 10, Exceptional, (1002)
"Excellent place to stay in Grand Junction. "
United States
Steve
Hotel Maverick
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in East Main Street

Find the best East Main Street areas for the activities you enjoy most.

Redlands

You'll enjoy the mountain views and wineries in Redlands. You might want to make time for a stop at Colorado National Monument or Redlands Mesa Golf Club.

Downtown

Though Downtown may not have many top sights, you can venture to the surrounding area to see attractions like Western Colorado Botanical Gardens and Bananas Fun Park.

Pear Park

While visiting Pear Park, you might make a stop by sights like Colorado River and James M. Robb – Colorado River State Park.

Historic Grand Junction

Visitors highly recommend Historic Grand Junction for its abundant dining options, and you can make a stop by Museum of the West while you're in town.

Horizon Drive District

Horizon Drive District might not have many top sights, but Grand Junction Motor Speedway and Canyon View Park are two attractions nearby that you can check out.

Top East Main Street Hotel Reviews

Ramada by Wyndham Grand Junction

Ramada by Wyndham Grand Junction

10/10 Excellent
"Good stay! Reasonable price "
Michael 1-night trip
Posted 1 day ago
Ramada by Wyndham Grand Junction

Frequently asked questions

What's it like in East Main Street?
Travellers will be sure to enjoy their time in Grand Junction's East Main Street neighbourhood.
How many hotels can I expect to find in the East Main Street area?
If you're searching for places to stay in Grand Junction, Expedia has something to meet your needs with 22 East Main Street hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in East Main Street, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to get the best deals in East Main Street.
What is there to do around this Grand Junction neighbourhood?
A few places to visit in the area around East Main Street include Museum of the West, Western Colorado Botanical Gardens and Elliott Tennis Center. While you're out sightseeing, Western Colorado Center for the Arts and Tennis Junction Indoor Center are a couple of additional sights to visit in Grand Junction.

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