Defiance hotels from RM281

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Our top choices for Defiance hotels

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
Fenton
8.0 out of 10, Very good, (1,157 reviews)
"Everything was great for overnight stay. "
United States
Regina
The price is RM354
RM409 total
includes taxes & fees
22 Apr - 23 Apr
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Baymont by Wyndham Warrenton

Baymont by Wyndham Warrenton
2.5 star property
Warrenton
7.6 out of 10, Good, (1,002 reviews)
"The front desk stuff were nice and welcoming. The room was clean and the breakfast was great. "
United States
Dan
The price is RM326
RM373 total
includes taxes & fees
2 Apr - 3 Apr
Baymont by Wyndham Warrenton

Super 8 by Wyndham Warrenton

Super 8 by Wyndham Warrenton
2.0 star property
Warrenton
7.4 out of 10, Good, (635 reviews)
"The parking was easy, the room was verry clean."
United States
Gary
The price is RM216
RM246 total
includes taxes & fees
7 Apr - 8 Apr
Super 8 by Wyndham Warrenton

WoodSpring Suites St Peters-OFallon

WoodSpring Suites St Peters-OFallon
2.5 star property
St. Peters
8.8 out of 10, Excellent, (62 reviews)
"Staff was very friendly "
United States
Jessica
The price is RM353
RM418 total
includes taxes & fees
2 Apr - 3 Apr
WoodSpring Suites St Peters-OFallon

Drury Inn & Suites Southwest St. Louis

Drury Inn & Suites Southwest St. Louis
3.0 star property
Valley Park
9.6 out of 10, Exceptional, (1,009 reviews)
"Very clean place with great food and friendly staff. "
Canada
Kara
The price is RM456
RM533 total
includes taxes & fees
3 Apr - 4 Apr
Drury Inn & Suites Southwest St. Louis

Quality Inn Foristell

Quality Inn Foristell
2.5 star property
Foristell
8.2 out of 10, Very good, (955 reviews)
"Comfy beds, but the trim, doors, and other finishings look pretty rough and in need of replacement. Simple enough breakfast and was just there for a night to sleep so it did the job."
United States
Laura
The price is RM360
RM406 total
includes taxes & fees
16 Apr - 17 Apr
Quality Inn Foristell

Wingate by Wyndham St. Louis/Fenton Route 66

Wingate by Wyndham St. Louis/Fenton Route 66
3.0 star property
Fenton
7.8 out of 10, Good, (1,169 reviews)
"Great location, comfy and clean rooms "
United States
Nestor
The price is RM337
RM389 total
includes taxes & fees
1 Apr - 2 Apr
Wingate by Wyndham St. Louis/Fenton Route 66

The Wildwood Hotel

The Wildwood Hotel
3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1,631 reviews)
"Staff was wonderful, location is great for our needs, and it was a quiet stay-which we loved. "
United States
Jessica
The price is RM352
RM410 total
includes taxes & fees
6 Apr - 7 Apr
The Wildwood Hotel

Holiday Inn Express & Suites Wentzville St Louis West by IHG

Holiday Inn Express & Suites Wentzville St Louis West by IHG
2.5 star property
Wentzville
9.4 out of 10, Exceptional, (884 reviews)
"Best breakfast setup I’ve ever experienced!"
United States
Lindsay
The price is RM575
RM684 total
includes taxes & fees
12 Apr - 13 Apr
Holiday Inn Express & Suites Wentzville St Louis West by IHG

Hampton Inn St. Charles St. Peters

Hampton Inn St. Charles St. Peters
2.5 star property
St. Charles
8.0 out of 10, Very good, (1,001 reviews)
"Everything was great as always at this location as i have stayed here many times"
United States
Gregory
The price is RM422
RM486 total
includes taxes & fees
12 Apr - 13 Apr
Hampton Inn St. Charles St. Peters

Hampton Inn St. Louis Wentzville

Hampton Inn St. Louis Wentzville
2.5 star property
Wentzville
9.0 out of 10, Wonderful, (676 reviews)
"Property very clean staff was super helpful with questions. Would recommend this place! Breakfast was great!"
United States
Melissa
The price is RM504
RM577 total
includes taxes & fees
7 Apr - 8 Apr
Hampton Inn St. Louis Wentzville

Best Western Plus Washington Hotel

Best Western Plus Washington Hotel
2.5 star property
Washington
9.2 out of 10, Wonderful, (669 reviews)
"Great stay and accommodations. The pool was very nice. "
United States
Shane
The price is RM511
RM582 total
includes taxes & fees
29 Mar - 30 Mar
Best Western Plus Washington Hotel

Super 8 by Wyndham St Charles

Super 8 by Wyndham St Charles
2.0 star property
St. Charles
8.0 out of 10, Very good, (1,000 reviews)
"Hotel was clean. Located in a good area, would stay here again. "
United States
Christy
The price is RM334
RM383 total
includes taxes & fees
2 Apr - 3 Apr
Super 8 by Wyndham St Charles

Comfort Suites St Charles - St Louis

Comfort Suites St Charles - St Louis
2.5 star property
St. Charles
8.4 out of 10, Very good, (1,002 reviews)
"Over all our stay was good. The room was a good size, we are thankful there was an ironing board and iron in the room. Good options at breakfast and the staff we encountered we are very pleasant. "
United States
Elizabeth
The price is RM378
RM434 total
includes taxes & fees
26 Apr - 27 Apr
Comfort Suites St Charles - St Louis

Drury Inn & Suites St. Louis St. Peters

Drury Inn & Suites St. Louis St. Peters
3.0 star property
St. Peters
9.4 out of 10, Exceptional, (1,000 reviews)
"Great stay! Very clean and staff was very nice. Definitely will be staying there on my return visit to the area!"
United States
Roxanne
The price is RM439
RM505 total
includes taxes & fees
19 Apr - 20 Apr
Drury Inn & Suites St. Louis St. Peters

Comfort Inn & Suites St. Louis - O'Fallon

Comfort Inn & Suites St. Louis - O'Fallon
2.5 star property
O'Fallon
7.6 out of 10, Good, (1,006 reviews)
"Good spot and great location to visit with family "
United States
Ernest
The price is RM321
RM379 total
includes taxes & fees
19 Apr - 20 Apr
Comfort Inn & Suites St. Louis - O'Fallon

Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1,003 reviews)
"Comfortable stay"
United States
Rebecca
The price is RM323
RM380 total
includes taxes & fees
16 Apr - 17 Apr
Sleep Inn & Suites O'Fallon MO - Technology Drive

Quality Inn Near Six Flags St. Louis

Quality Inn Near Six Flags St. Louis
2.5 star property
Pacific
8.4 out of 10, Very good, (367 reviews)
"Excellent staff & very clean room"
United States
Karen
The price is RM395
RM453 total
includes taxes & fees
5 Apr - 6 Apr
Quality Inn Near Six Flags St. Louis

Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
O'Fallon
8.6 out of 10, Excellent, (889 reviews)
"It was a wonderful stay for my girls and her birthday. She had a blast and the room was Lovely 😍🌹"
United States
Amanda
The price is RM408
RM482 total
includes taxes & fees
2 Apr - 3 Apr
Holiday Inn Express St. Louis West - O'Fallon by IHG

Best Western Plus Fenton

Best Western Plus Fenton
2.5 star property
Fenton
9.2 out of 10, Wonderful, (242 reviews)
"The lady at the front desk was amazing!"
United States
Thomas
The price is RM428
RM494 total
includes taxes & fees
9 Apr - 10 Apr
Best Western Plus Fenton
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Defiance attractions

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

A covered bridge at the Historic Daniel Boone Home Park in Defiance, Missouri

Top Defiance Hotel Reviews

More cheap stays in Defiance

Frequently asked questions

What's the best place to stay in Defiance?
Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham and The Wildwood Hotel. See all available top hotels, or vacation rentals in Defiance.
If I need to cancel my hotel reservation in Defiance, will I receive a refund?
Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.
What are some accommodation options with pools in Defiance?
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham: Offers an indoor pool, an outdoor pool and buffet. The Wildwood Hotel and Ameristar Casino Resort and Spa are two additional hotels with an on-site pool. View all hotels with pools in Defiance.
How is it staying in Defiance?
Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station, Enterprise Center and Busch Stadium. In Defiance, there are 19 hotels and other accommodation options to choose from. Find out more about Defiance.
What should I do while I'm visiting Defiance?
Natural beauty is on display at Matson Hill Park Trailhead, August A. Busch Memorial Conservation Area and Missouri River. A couple of additional sights to add to your itinerary are Chandler Hill Vineyards and Historic Daniel Boone Home and Heritage Center. Take a look at what more there is to see and do in Expedia's Defiance guide.
What's the weather like in Defiance?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

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