Defiance hotels from RM 258

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Go beyond your typical stay in Defiance

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Pool
Pool

Check prices for these dates

Tonight
10 Nov - 11 Nov
Tomorrow
11 Nov - 12 Nov
This weekend
13 Nov - 15 Nov
Next weekend
20 Nov - 22 Nov

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Our top choices for Defiance hotels

A multi-story hotel with a mix of brick and siding exteriors, multiple windows, and a well-maintained lawn.

1. Holiday Inn Express St. Louis West - O'Fallon by IHG

Holiday Inn Express St. Louis West - O'Fallon by IHG
2.5 star property
O'Fallon
8.4 out of 10, Very good, (1,003 reviews)
"This was a clean, safe and convenient place to stay while traveling through St. Louis."
United States
Greg
The price is RM410
RM483 total
includes taxes & fees
15 Nov - 16 Nov
Holiday Inn Express St. Louis West - O'Fallon by IHG
A hotel room with a bed, a sofa, a coffee table, and wall art.

2. Sleep Inn & Suites O'Fallon MO - Technology Drive

Sleep Inn & Suites O'Fallon MO - Technology Drive
2.5 star property
O'Fallon
9.0 out of 10, Wonderful, (1,158 reviews)
"Rooms are very clean, the staff is friendly and the location is great. We enjoyed are stay."
United States
Matthew
The price is RM331
RM391 total
includes taxes & fees
3 Dec - 4 Dec
Sleep Inn & Suites O'Fallon MO - Technology Drive
A hotel entrance with a stone facade, a wooden archway, and a paved walkway.

3. Staybridge Suites O'Fallon Chesterfield by IHG

Staybridge Suites O'Fallon Chesterfield by IHG
3.0 star property
O'Fallon
8.4 out of 10, Very good, (489 reviews)
"We were very happy with our stay. The room exceeded our expectations. The beds were comfortable. It was very clean, and it also smelled good! We will definitely stay here again."
United States
Sal
The price is RM479
RM565 total
includes taxes & fees
30 Nov - 1 Dec
Staybridge Suites O'Fallon Chesterfield by IHG
An outdoor patio area with a stone fire pit, wicker furniture, and a covered seating area with a view of the building's interior.

4. TownePlace Suites by Marriott St. Louis Chesterfield

TownePlace Suites by Marriott St. Louis Chesterfield
3.0 star property
Chesterfield
9.0 out of 10, Wonderful, (336 reviews)
"Excellent 1 night stay. Clean and comfortable"
United States
Thomas
The price is RM495
RM581 total
includes taxes & fees
15 Nov - 16 Nov
TownePlace Suites by Marriott St. Louis Chesterfield
A spacious lobby with a stone fireplace, seating area, and a bar with high stools.

5. Residence Inn by Marriott O'Fallon

Residence Inn by Marriott O'Fallon
3.0 star property
O'Fallon
8.4 out of 10, Very good, (509 reviews)
"Beautiful room, very clean with nice staff"
United States
Rianna
The price is RM532
RM627 total
includes taxes & fees
24 Nov - 25 Nov
Residence Inn by Marriott O'Fallon
A hotel with a prominent tower, a fountain in the courtyard, and a well-maintained garden.

6. The Wildwood Hotel

The Wildwood Hotel
3.5 star property
Wildwood
9.2 out of 10, Wonderful, (1,683 reviews)
"Clean, quiet, great continental breakfast, and close to several places to eat."
United States
Lori
The price is RM325
RM378 total
includes taxes & fees
8 Dec - 9 Dec
The Wildwood Hotel
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

7. Comfort Inn & Suites Chesterfield - St. Louis

Comfort Inn & Suites Chesterfield - St. Louis
2.5 star property
Chesterfield
7.8 out of 10, Good, (1,007 reviews)
"Mindy was very nice. Bed not so much, please keep a smoke detector in the room instead of taking it apart."
United States
Charissa
The price is RM337
RM407 total
includes taxes & fees
29 Nov - 30 Nov
Comfort Inn & Suites Chesterfield - St. Louis
A spacious lobby with a high ceiling, a central seating area with sofas and a coffee table, and a large window providing natural light.

8. Hilton Garden Inn St. Louis/O'Fallon MO

Hilton Garden Inn St. Louis/O'Fallon MO
3.0 star property
O'Fallon
8.8 out of 10, Excellent, (768 reviews)
"Everything you could need for an overnight or extended stay. Staff was extremely helpful, and the property is well-maintained."
United States
Duane
The price is RM483
RM572 total
includes taxes & fees
3 Dec - 4 Dec
Hilton Garden Inn St. Louis/O'Fallon MO
A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

9. Hyatt Place St. Louis/Chesterfield

Hyatt Place St. Louis/Chesterfield
3.0 star property
Chesterfield
9.6 out of 10, Exceptional, (1,014 reviews)
"Very nice hotel and lovely room"
United States
Karin
The price is RM526
RM610 total
includes taxes & fees
15 Nov - 16 Nov
Hyatt Place St. Louis/Chesterfield
An outdoor patio area with wicker furniture and a central fire feature.

10. Courtyard by Marriott St. Louis Chesterfield

Courtyard by Marriott St. Louis Chesterfield
3.0 star property
Chesterfield
9.0 out of 10, Wonderful, (684 reviews)
"The room was beautiful and clean. We enjoyed the pool and the bar while we were there. Great amenities!"
United States
Brittney
The price is RM445
RM518 total
includes taxes & fees
19 Nov - 20 Nov
Courtyard by Marriott St. Louis Chesterfield
A modern dining area with a long table and chairs, a flat-screen TV mounted on the wall, and a wooden ceiling.

11. Holiday Inn Express & Suites St. Louis - Chesterfield by IHG

Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
2.5 star property
Chesterfield
9.0 out of 10, Wonderful, (1,001 reviews)
"We drove across America and this property stood out by just having the most comfortable beds and a great breakfast , great staff ."
United States
Terry
The price is RM446
RM519 total
includes taxes & fees
19 Nov - 20 Nov
Holiday Inn Express & Suites St. Louis - Chesterfield by IHG
A spacious lobby with a central round table, two sofas, and a chandelier.

12. Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield
3.0 star property
Chesterfield
9.6 out of 10, Exceptional, (1,322 reviews)
"This was by far one of the nicest places we have stayed in."
United States
Linda
The price is RM528
RM612 total
includes taxes & fees
15 Nov - 16 Nov
Drury Plaza Hotel St. Louis Chesterfield
A modern hotel dining area with a long communal table, multiple chairs, and pendant lighting.

13. Hampton Inn & Suites St. Louis/Chesterfield

Hampton Inn & Suites St. Louis/Chesterfield
3.5 star property
Chesterfield
8.8 out of 10, Excellent, (923 reviews)
"Incredibly clean and modern room and building. Friendly and helpful front desk staff, free shuttle (so helpful), and super close to a bunch of stuff. Would stay again, for longer next time!"
United States
Ellen
The price is RM445
RM518 total
includes taxes & fees
29 Nov - 30 Nov
Hampton Inn & Suites St. Louis/Chesterfield
A spacious lobby with a grand staircase, a fireplace, and comfortable seating areas.

14. Holiday Inn St. Louis West Six Flags by IHG

Holiday Inn St. Louis West Six Flags by IHG
3.0 star property
Eureka
9.0 out of 10, Wonderful, (1,001 reviews)
"Great hotel!"
United States
Rob
The price is RM532
RM619 total
includes taxes & fees
30 Nov - 1 Dec
Holiday Inn St. Louis West Six Flags by IHG
An outdoor patio with a built-in grill, seating area, and stone walls.

15. Residence Inn by Marriott St. Louis Chesterfield

Residence Inn by Marriott St. Louis Chesterfield
3.0 star property
Chesterfield
9.6 out of 10, Exceptional, (264 reviews)
"Would stay here again!"
United States
Chelsea
The price is RM767
RM897 total
includes taxes & fees
20 Nov - 21 Nov
Residence Inn by Marriott St. Louis Chesterfield
A spacious lobby with a brown leather sofa, multiple chairs, a coffee table with a skull decoration, and a large chandelier.

16. DoubleTree by Hilton Hotel St. Louis - Chesterfield

DoubleTree by Hilton Hotel St. Louis - Chesterfield
4.0 star property
Chesterfield
8.8 out of 10, Excellent, (1,004 reviews)
"Hotel staff were kind and accommodating. Great stay for a great price!"
United States
April
The price is RM444
RM515 total
includes taxes & fees
27 Nov - 28 Nov
DoubleTree by Hilton Hotel St. Louis - Chesterfield
A hotel named Sonesta ES Suites with a staircase leading to the entrance, surrounded by well-maintained greenery and red flowers.

17. Sonesta ES Suites St. Louis - Chesterfield

Sonesta ES Suites St. Louis - Chesterfield
3.0 star property
Chesterfield
8.0 out of 10, Very good, (1,067 reviews)
"Breakfast was great"
United States
Shuntichia
The price is RM376
RM436 total
includes taxes & fees
24 Nov - 25 Nov
Sonesta ES Suites St. Louis - Chesterfield
A hotel room with a bed, desk, TV, and a view of the outdoors.

18. Fairfield Inn & Suites by Marriott St. Louis Chesterfield

Fairfield Inn & Suites by Marriott St. Louis Chesterfield
3.0 star property
Chesterfield
9.0 out of 10, Wonderful, (1,004 reviews)
"very nice stay. Great room with easy check in ,nice staff, friendly and helpful. Excellent breakfast, with good setup and fresh food."
United States
Charles
The price is RM435
RM504 total
includes taxes & fees
19 Nov - 20 Nov
Fairfield Inn & Suites by Marriott St. Louis Chesterfield
An indoor swimming pool with a hot tub, clear signage, and a view of the outside through large windows.

19. Comfort Inn Near Six Flags St. Louis

Comfort Inn Near Six Flags St. Louis
2.5 star property
Pacific
8.4 out of 10, Very good, (1,002 reviews)
"The breakfast was mediocre and there was road noise but other than that, it was a nice stay."
United States
Scott
The price is RM353
RM404 total
includes taxes & fees
1 Dec - 2 Dec
Comfort Inn Near Six Flags St. Louis
A spacious lobby with a high ceiling, a dining area, and a kitchen in the background.

20. Quality Inn Near Six Flags St. Louis

Quality Inn Near Six Flags St. Louis
2.5 star property
Pacific
8.4 out of 10, Very good, (413 reviews)
"Great hotel and Breakfast is nothing special but it makes sense for the price you pay."
United States
Chantelle
The price is RM343
RM393 total
includes taxes & fees
30 Nov - 1 Dec
Quality Inn Near Six Flags St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare top hotels in Defiance

A multi-story hotel with a mix of brick and siding exteriors, multiple windows, and a well-maintained lawn.

Holiday Inn Express St. Louis West - O'Fallon by IHG

2.5 star property
O'Fallon
View
A hotel room with a bed, a sofa, a coffee table, and wall art.

Sleep Inn & Suites O'Fallon MO - Technology Drive

2.5 star property
O'Fallon
View
A hotel entrance with a stone facade, a wooden archway, and a paved walkway.

Staybridge Suites O'Fallon Chesterfield by IHG

3.0 star property
O'Fallon
View
An outdoor patio area with a stone fire pit, wicker furniture, and a covered seating area with a view of the building's interior.

TownePlace Suites by Marriott St. Louis Chesterfield

3.0 star property
Chesterfield
View
A spacious lobby with a stone fireplace, seating area, and a bar with high stools.

Residence Inn by Marriott O'Fallon

3.0 star property
O'Fallon
View
8.4
Very good
1,003 reviews
9.0
Wonderful
1,158 reviews
8.4
Very good
489 reviews
9.0
Wonderful
336 reviews
8.4
Very good
509 reviews
The price is RM410
RM483 total
includes taxes & fees
15 Nov - 16 Nov
The price is RM331
RM391 total
includes taxes & fees
3 Dec - 4 Dec
The price is RM479
RM565 total
includes taxes & fees
30 Nov - 1 Dec
The price is RM495
RM581 total
includes taxes & fees
15 Nov - 16 Nov
The price is RM532
RM627 total
includes taxes & fees
24 Nov - 25 Nov
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • No Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking
  • Yes, Breakfast included
  • Yes, Pool
  • No Spa
  • Yes, Pet-friendly
  • Yes, WiFi included
  • Yes, Parking

Stay near popular Defiance attractions

A glass of red wine on a wooden table with a vineyard in the background.
Photo by Pages of Travel
Open Photo by Pages of Travel

Chandler Hill Vineyards

7.8/10 (7 reviews)
This elegant Missouri winery showcases local and California wines from its hillside setting. Savour varietals on the expansive terrace while enjoying vineyard views and seasonal cuisine from their full-service kitchen.
See properties

Learn more about Defiance

Nestled along the Missouri River, this historic village offers scenic hiking trails and access to nearby wine country. Visit the Daniel Boone Home in neighbouring Defiance Township or enjoy tastings at the family-owned wineries dotting the surrounding countryside.

See all hotels in Defiance
A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

Frequently Asked Questions

If I need to cancel my hotel reservation in Defiance, will I receive a refund?

Yes! The majority of room reservations are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Defiance.

What are some accommodation options with pools in Defiance?

Sonesta ES Suites St. Louis - Chesterfield: Offers daily, a seasonal outdoor pool and free self parking. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham and Ameristar Casino Resort and Spa are two additional hotels with an on-site pool. View all hotels with pools in Defiance.

How is it staying in Defiance?

Visitors can enjoy all that Defiance has to offer, including the wineries and parks. Top sights in the area include St. Louis Union Station and St. Louis Zoo. In Defiance, there are 19 hotels and other accommodation options to choose from. Find out more about Defiance.

What should I do while I'm visiting Defiance?

Natural beauty is on display at August A. Busch Memorial Conservation Area, Missouri River and Matson Hill Park Trailhead. A couple of additional sights to add to your itinerary are Yellow Farmhouse Winery and Chandler Hill Vineyards. Take a look at what more there is to see and do in Expedia's Defiance guide.

What's the weather like in Defiance?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.

What's the best place to stay in Defiance?

Hollywood Casino & Hotel St. Louis, located 18.1 mi (29.2 km) from the heart of Defiance, is a top choice for your stay, based on our traveller data. Two other options for your visit to the area are Sonesta ES Suites St. Louis - Chesterfield and Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham. See all available top hotels, or vacation rentals in Defiance.