𝗧𝗢𝗣 𝗛𝗼𝘁𝗲𝗹𝘀 𝗶𝗻 Commerce from RM269 (2026) - Fully Refundable Options

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Our top choices for Commerce hotels

A modern living room with a sofa, armchairs, a coffee table, and a TV mounted on the wall.

An indoor swimming pool with lounge chairs and tables, large windows, and a view of the outside.

A reception area with a wooden reception desk, a glass door leading to a storage room, and a decorative wall piece.

A modern living room with a sofa, a coffee table, and a dining area with chairs and a table.

1. Fairfield Inn & Suites by Marriott Cape Girardeau

Cape Girardeau

Carlos

RM413

RM466 total

includes taxes & fees

25 Oct - 26 Oct

A hotel room with a blue sofa, an orange ottoman, a desk with a lamp, a television, and a window with curtains.

A Dear Tree Inn building with a covered entrance and a clear sky at dusk.

A reception area with a wooden reception desk, two blue armchairs with orange cushions, a patterned side table, and a wall-mounted lamp.

A hotel room with two beds, a window with curtains, an air conditioning unit, and a lamp on a nightstand.

2. Pear Tree Inn Cape Girardeau West

Cape Girardeau

Elizabeth

RM294

RM331 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.

An indoor swimming pool with a clear view of the pool area, including the pool's edge, a set of stairs leading into the pool, and a few lounge chairs and tables around the pool.

A hotel room with a bed, desk, chair, TV, and a small kitchenette area.

A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.

3. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Cape Girardeau

ELAINE

RM404

RM460 total

includes taxes & fees

29 Oct - 30 Oct

A hotel room with a large bed, two bedside lamps, a chair, and a wooden headboard.

A hotel room with a large bed, two bedside tables, a desk with a chair, and two lamps.

A bowl of cereal with raisins and milk, a half orange, and a sandwich on a table with a yellow napkin.

A plate of mixed greens salad with cherry tomatoes and croutons, a bowl of baked pasta, and a glass of red wine on a wooden table.

4. Drury Inn & Suites Cape Girardeau

Cape Girardeau

Teresa

RM371

RM419 total

includes taxes & fees

14 Oct - 15 Oct

A spacious lobby with a circular seating area, a stone fireplace, and modern lighting fixtures.

A spacious lobby with a curved seating area, a reception desk, and a large window providing natural light.

A spacious corridor with a high ceiling, recessed lighting, and a series of posters on the walls.

An indoor swimming pool with clear blue water, surrounded by beige walls and large windows.

5. Drury Plaza Hotel Cape Girardeau Conference Center

Cape Girardeau

Sandra

RM408

RM460 total

includes taxes & fees

5 Oct - 6 Oct

A hotel entrance with a large sign reading "LAQUINTA" and a sun graphic.

An outdoor patio with tables and chairs, a stone wall, and large windows.

A breakfast bar with a coffee machine, waffle maker, toaster, and various food items.

A hotel room with two beds, a nightstand, a lamp, and a chair.

6. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Jackson

Elaine

RM329

RM357 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a curved staircase, large windows, and a seating area with a rug.

A modern outdoor seating area with a fire feature, a stone wall, and a view of the sunset.

A modern living room with a large sectional sofa, a flat-screen TV, and a view of the sea through large windows.

A modern bar area with a herringbone patterned wall, a long counter with bar stools, and a variety of bottles and glasses.

7. The Riverview

Cape Girardeau

Alyssa

RM466

RM526 total

includes taxes & fees

4 Oct - 5 Oct

A spacious dining area with high ceilings, large windows, and modern lighting fixtures.

A hotel room with a bed, a desk with a television, a chair, a suitcase, and a map on the wall.

A gym with exercise equipment, a treadmill, and a wall-mounted TV.

An outdoor patio with stone walls, wicker furniture, and large windows.

8. Hampton Inn Cape Girardeau I 55 East

Cape Girardeau

Rebekah

RM432

RM487 total

includes taxes & fees

25 Oct - 26 Oct

A modern retail area with a display of local items and snacks.

An outdoor patio area with seating arrangements, including a sofa and chairs, and a table.

A hotel room with two beds, a desk, a chair, a TV, and a window with a view.

A modern lounge area with seating options including sofas, chairs, and a hanging chair, with large windows providing a view of the outdoors.

9. Tru By Hilton Cape Girardeau

Cape Girardeau

Shannon

RM365

RM415 total

includes taxes & fees

25 Oct - 26 Oct

A spacious lobby with marble flooring, elegant seating, and a grand staircase.

A modern hotel lobby with a framed advertisement for breakfast at the new Bistro, a seating area with sofas and a coffee table, and a decorative mirror reflecting the space.

A lobby with seating areas, a reception desk, and a bar.

A Courtyard by Marriott hotel with a modern brick facade, large windows, and a covered entrance area.

10. Courtyard by Marriott Cape Girardeau Downtown

Cape Girardeau

Kristin

RM510

RM578 total

includes taxes & fees

12 Oct - 13 Oct

A building with a fountain and flower beds in front.

A reception area with a stone wall, wooden cabinets, and a sign for The Riverstone Hotel.

A hotel room with a large bed, two bedside tables with lamps, a chair, a small table, and a picture on the wall.

A modern kitchen with dark wooden cabinets, a central island, and a ceiling fan.

11. The Riverstone Hotel Charleston-Sikeston

Charleston

Kathleen

RM271

RM301 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with a large bed, two bedside lamps, a framed picture of a bridge, and a wooden nightstand with a phone.

A reception area with a sofa, a coffee table, a potted plant, and a framed picture on the wall.

A reception area with a counter, a flat-screen TV, and a window with blinds.

A restaurant with wooden cabinets, a refrigerator, and a counter with various items. There are tables and chairs for dining.

12. Super 8 by Wyndham Charleston/Sikeston East MO

Charleston

William

RM243

RM269 total

includes taxes & fees

4 Oct - 5 Oct

A hotel lobby with a reception desk, seating area, and a large window.

A hotel room with a desk, chair, television, and a lamp.

A hotel lobby with a reception desk, two armchairs, a coffee table, and large windows with potted plants.

A hotel room with two beds, a desk with a computer, a television, and a window with curtains.

13. Quality Inn Cairo I-57

Cairo

Santiago

RM278

RM309 total

includes taxes & fees

16 Oct - 17 Oct

An indoor swimming pool with a 3 FT depth marker, a metal ladder, and a tiled floor.

A spacious lobby with a polished floor, seating areas, and modern lighting fixtures.

An outdoor seating area with sofas and planters, surrounded by a building with large windows and a brick wall.

A hotel room with a patterned sofa, a yellow ottoman, a desk with a TV, and a framed picture on the wall.

14. Drury Inn & Suites Sikeston, MO

Sikeston

Scott

RM384

RM441 total

includes taxes & fees

27 Oct - 28 Oct

A hotel with a modern design, featuring a prominent sign for Candlewood Suites. There are multiple parking spaces visible in front of the building.

A hotel entrance with a large tree, a well-maintained garden with various plants and flowers, and a parking lot.

A hotel patio with a gazebo, outdoor seating, and a view of the road.

A hotel room with a bed, a TV, a desk, and a chair.

15. Candlewood Suites Cape Girardeau by IHG

Cape Girardeau

Samuel

RM347

RM414 total

includes taxes & fees

11 Oct - 12 Oct

A spacious living area with a high ceiling, a green accent wall, and a wooden balcony railing.

A reception desk with a green wall, a wooden door, and a sign that reads 'QUALITY INN.'

A hotel room with a flat-screen TV, a microwave, a sofa, a lamp, and a window with curtains.

A hotel room with a large bathtub, a bed with a wooden headboard, a nightstand with a lamp, and a painting of a building on the wall.

16. Quality Inn Cape Girardeau North

Cape Girardeau

Danny

RM243

RM274 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with large windows, comfortable seating, and a modern ceiling design.

A breakfast bar with coffee machines, a cereal dispenser, and a fruit display.

A hotel room with a bed, a dark sofa, an ottoman, a lamp, and artwork on the wall.

A gym with treadmills, an elliptical, a bench, and a rack of dumbbells.

17. Comfort Suites Jackson-Cape Girardeau

Jackson

VICTORIA

RM309

RM334 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, desk, chair, television, and two wall-mounted lamps.

A hotel room with a kitchenette, a bed, a dining table with chairs, a TV mounted on the wall, and a dresser.

A motel with multiple floors, a parking lot, and a staircase leading to the upper floors.

A hotel room with a large bed, two bedside tables, a nightstand, a telephone, and two wall-mounted lamps.

18. Town House Inn Cape Giradreau

Cape Girardeau

Joshua

RM286

RM334 total

includes taxes & fees

2 Oct - 3 Oct

A hotel room with a large bed, a desk, a television, and a bathroom visible through an open door.

A bathroom with a sink, mirror, towel rack, shower, and toilet.

A kitchen with wooden cabinets, a granite countertop, a built-in microwave, and a window with a view.

A hotel room with two beds, a nightstand, a lamp, and a window with curtains.

19. Eagle Inn Charleston

Charleston

Jackson

RM269

RM299 total

includes taxes & fees

29 Oct - 30 Oct

A hotel room with two beds, a desk, a chair, a TV, and a mirror.

A motel with a blue awning and a green 7-Eleven. It has a covered parking area and a two-story structure with a balcony.

A reception area with a counter, a coffee machine, and seating.

A reception area with a sofa, a small table, a trash bin, a microwave, and a book display.

20. Country Yard Inn and Suite

Sikeston

William

RM250

RM297 total

includes taxes & fees

2 Oct - 3 Oct

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Top Commerce Hotel Reviews

Drury Inn & Suites Sikeston, MO

10/10 Excellent

"EVERYONE was EXTREMELY FRIENDLY"

Quality Inn Cape Girardeau North

10/10 Excellent

"Great place great breakfast great room staff was great"

Candlewood Suites Cape Girardeau by IHG

10/10 Excellent

"trodo estubo excelente gracias por sus servicios"

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

10/10 Excellent

"Clean rooms. Nice breakfast. Very nice staff."

Drury Inn & Suites Cape Girardeau

10/10 Excellent

"Upgraded to a 2 room suite. Rey nice room lots of storage. Would definitely stay here again."

Hampton Inn Cape Girardeau I 55 East

8/10 Good

"Liked the cleanliness of the room, and every time my family left or when returning to our room the staff said hello. What I didn’t like there were a lot of ants in the room where the especially by the TV and desks."

Courtyard by Marriott Cape Girardeau Downtown

10/10 Excellent

"Very nice! Bed was comfortable and room had a very large bathroom and shower. Towels were thick and fluffy. Enjoyed having a bar downstairs with a fun friendly staff. Will stay there again when I’m coming through."

Town House Inn Cape Giradreau

8/10 Good

"The outside needed cleaning, but the room was very clean and well maintained."

More cheap stays in Commerce

Super 8 by Wyndham Charleston/Sikeston East MO

310 S Story St Charleston MO

RM243

RM269 total

13 Oct - 14 Oct

includes taxes & fees

Quality Inn Cape Girardeau North

2011 North Kingshighway Cape Girardeau MO

RM243

RM274 total

1 Nov - 2 Nov

includes taxes & fees

7/10 Good! (801 reviews)

Pear Tree Inn Cape Girardeau West

103 Cape West Pkwy Cape Girardeau MO

RM294

RM331 total

25 Oct - 26 Oct

includes taxes & fees

Candlewood Suites Cape Girardeau by IHG

485 S Mount Auburn Rd Cape Girardeau MO

RM347

RM414 total

11 Oct - 12 Oct

includes taxes & fees

8/10 Very good! (1,000 reviews)

Tru By Hilton Cape Girardeau

2520 Veterans Memorial Dr Cape Girardeau MO

RM365

RM415 total

25 Oct - 26 Oct

includes taxes & fees

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

3253 William Street Cape Girardeau MO

RM404

RM460 total

29 Oct - 30 Oct

includes taxes & fees

Frequently asked questions

What's the best place to stay in Commerce?

Drury Plaza Hotel Cape Girardeau Conference Center, located 12.6 mi (20.3 km) from the heart of Commerce, is a top choice for your stay, based on our traveller data. Two other choices for your visit to the area are Pear Tree Inn Cape Girardeau West and The Riverview. See all available top hotels, or vacation rentals in Commerce.

If I need to cancel my hotel reservation in Commerce, will I receive a refund?

Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Commerce.

How is it to stay in Commerce?

Travellers to Commerce will find plenty to explore and enjoy. There are 88 hotels and other accommodation options in the surrounding area. Find out more about Commerce.

What should I see while I'm in Commerce?

A favourite place to visit is Mississippi River. You'll also find Century Casino & Hotel Cape Girardeau and Show Me Center in the area. Take a look at what more there is to see and do in Expedia's Commerce guide.

What's the seasonal weather in Commerce?

The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Commerce is 1491 mm.

Commerce hotels from RM269

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Commerce

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Commerce hotels

1. Fairfield Inn & Suites by Marriott Cape Girardeau

2. Pear Tree Inn Cape Girardeau West

3. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

4. Drury Inn & Suites Cape Girardeau

5. Drury Plaza Hotel Cape Girardeau Conference Center

6. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

7. The Riverview

8. Hampton Inn Cape Girardeau I 55 East

9. Tru By Hilton Cape Girardeau

10. Courtyard by Marriott Cape Girardeau Downtown

11. The Riverstone Hotel Charleston-Sikeston

12. Super 8 by Wyndham Charleston/Sikeston East MO

13. Quality Inn Cairo I-57

14. Drury Inn & Suites Sikeston, MO

15. Candlewood Suites Cape Girardeau by IHG

16. Quality Inn Cape Girardeau North

17. Comfort Suites Jackson-Cape Girardeau

18. Town House Inn Cape Giradreau

19. Eagle Inn Charleston

20. Country Yard Inn and Suite

Top Commerce Hotel Reviews

Drury Inn & Suites Sikeston, MO

Quality Inn Cape Girardeau North

Candlewood Suites Cape Girardeau by IHG

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

Drury Inn & Suites Cape Girardeau

Hampton Inn Cape Girardeau I 55 East

Courtyard by Marriott Cape Girardeau Downtown

Town House Inn Cape Giradreau

More cheap stays in Commerce

Super 8 by Wyndham Charleston/Sikeston East MO

Quality Inn Cape Girardeau North

Pear Tree Inn Cape Girardeau West

Candlewood Suites Cape Girardeau by IHG

Tru By Hilton Cape Girardeau

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Frequently asked questions

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