Hotels near Appleton Medical Center

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
27 Dec - 28 Dec
Tomorrow
28 Dec - 29 Dec
Next weekend
2 Jan - 4 Jan
In two weeks
9 Jan - 11 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Appleton Medical Center hotels

Premium bedding, minibar, in-room safe, iron/ironing board
CopperLeaf Boutique Hotel & Spa, BW Premier Collection

CopperLeaf Boutique Hotel & Spa, BW Premier Collection

CopperLeaf Boutique Hotel & Spa, BW Premier Collection
3.5 star property
2.2 km from Appleton Medical Center
9.4 out of 10, Exceptional, (1001)
"Clean, good restaurant, nice staff "
Canada
Mark Anthony
The price is RM504
RM582 total
includes taxes & fees
7 Jan - 8 Jan 2026
CopperLeaf Boutique Hotel & Spa, BW Premier Collection
Desk, iron/ironing board, free WiFi, bed sheets
Courtyard by Marriott Appleton Riverfront

Courtyard by Marriott Appleton Riverfront

Courtyard by Marriott Appleton Riverfront
3.0 star property
2.1 km from Appleton Medical Center
9.4 out of 10, Exceptional, (433)
"We love this spot! The suites are sizable, the mattresses are outstanding and the scenery around it is beautiful. "
United States
Kathryn
The price is RM652
RM753 total
includes taxes & fees
9 Jan - 10 Jan 2026
Courtyard by Marriott Appleton Riverfront
Premium bedding, in-room safe, desk, rollaway beds
Hilton Appleton Paper Valley

Hilton Appleton Paper Valley

Hilton Appleton Paper Valley
3.5 star property
2.2 km from Appleton Medical Center
8.6 out of 10, Excellent, (1003)
"Nice rooms for the price "
United States
Tracie
The price is RM394
RM455 total
includes taxes & fees
25 Jan - 26 Jan 2026
Hilton Appleton Paper Valley
Indoor pool
Cambria Hotel Appleton

Cambria Hotel Appleton

Cambria Hotel Appleton
3.0 star property
3.2 km from Appleton Medical Center
8.8 out of 10, Excellent, (985)
"Comfy bed!"
United States
Nancy
The price is RM389
RM449 total
includes taxes & fees
30 Dec - 31 Dec
Cambria Hotel Appleton
Lobby
AmericInn by Wyndham Appleton North/Little Chute

AmericInn by Wyndham Appleton North/Little Chute

AmericInn by Wyndham Appleton North/Little Chute
2.0 star property
3.1 km from Appleton Medical Center
7.6 out of 10, Good, (1001)
"It was a great stay...."
United States
Kelly
The price is RM275
RM318 total
includes taxes & fees
5 Jan - 6 Jan 2026
AmericInn by Wyndham Appleton North/Little Chute
Restaurant
Hampton Inn Appleton-Fox River Mall Area

Hampton Inn Appleton-Fox River Mall Area

Hampton Inn Appleton-Fox River Mall Area
2.5 star property
6 km from Appleton Medical Center
9.4 out of 10, Exceptional, (1004)
"Clean room, good breakfast and friendly staff made our trip special"
United States
Michael
The price is RM345
RM399 total
includes taxes & fees
3 Jan - 4 Jan 2026
Hampton Inn Appleton-Fox River Mall Area
Lobby
Fairfield Inn & Suites by Marriott Appleton

Fairfield Inn & Suites by Marriott Appleton

Fairfield Inn & Suites by Marriott Appleton
3.5 star property
6.1 km from Appleton Medical Center
9.4 out of 10, Exceptional, (232)
"Front desk/check in was great! Kind and informative. Thank you!"
United States
Ashley
The price is RM360
RM416 total
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn & Suites by Marriott Appleton
Lobby
Cobblestone Hotel & Suites-Little Chute

Cobblestone Hotel & Suites-Little Chute

Cobblestone Hotel & Suites-Little Chute
3.0 star property
6.2 km from Appleton Medical Center
9.4 out of 10, Exceptional, (666)
"Good place to stay. "
United States
Kevin
The price is RM324
RM375 total
includes taxes & fees
29 Dec - 30 Dec
Cobblestone Hotel & Suites-Little Chute
Exterior
Home2 Suites by Hilton Appleton

Home2 Suites by Hilton Appleton

Home2 Suites by Hilton Appleton
3.0 star property
7.3 km from Appleton Medical Center
9.6 out of 10, Exceptional, (660)
"Great place. Clean. Nice pool. Great check in staff"
United States
peter
The price is RM399
RM460 total
includes taxes & fees
25 Jan - 26 Jan 2026
Home2 Suites by Hilton Appleton
Exterior
Holiday Inn Appleton by IHG

Holiday Inn Appleton by IHG

Holiday Inn Appleton by IHG
3.0 star property
6.5 km from Appleton Medical Center
9.2 out of 10, Wonderful, (495)
"Excellent service"
United States
Sarah
The price is RM385
RM444 total
includes taxes & fees
30 Dec - 31 Dec
Holiday Inn Appleton by IHG
Lobby
DoubleTree by Hilton Appleton

DoubleTree by Hilton Appleton

DoubleTree by Hilton Appleton
4.0 star property
6.2 km from Appleton Medical Center
9.0 out of 10, Wonderful, (1380)
"Great check in, fast and the warm cookie! Room was excellent. "
United States
Diane
The price is RM406
RM469 total
includes taxes & fees
1 Jan - 2 Jan 2026
DoubleTree by Hilton Appleton
Indoor pool, pool loungers
Comfort Suites Appleton Airport

Comfort Suites Appleton Airport

Comfort Suites Appleton Airport
2.5 star property
5.5 km from Appleton Medical Center
8.8 out of 10, Excellent, (921)
"Clean room and great staff!"
United States
Jeanine
The price is RM403
RM466 total
includes taxes & fees
26 Jan - 27 Jan 2026
Comfort Suites Appleton Airport
Exterior
Country Inn & Suites by Radisson, Appleton Airport - Fox River Mall Area

Country Inn & Suites by Radisson, Appleton Airport - Fox River Mall Area

Country Inn & Suites by Radisson, Appleton Airport - Fox River Mall Area
2.5 star property
6 km from Appleton Medical Center
8.8 out of 10, Excellent, (1003)
"All around nice place to stay."
United States
Peggy
The price is RM305
RM352 total
includes taxes & fees
3 Jan - 4 Jan 2026
Country Inn & Suites by Radisson, Appleton Airport - Fox River Mall Area
Indoor pool, pool loungers
AmericInn by Wyndham Appleton Downtown

AmericInn by Wyndham Appleton Downtown

AmericInn by Wyndham Appleton Downtown
2.5 star property
5 km from Appleton Medical Center
8.4 out of 10, Very good, (1002)
"Staff is very nice and accommodating we stay there every year."
United States
Linda
The price is RM281
RM324 total
includes taxes & fees
19 Jan - 20 Jan 2026
AmericInn by Wyndham Appleton Downtown
Fridge, microwave, stovetop, coffee/tea maker
Candlewood Suites Appleton by IHG

Candlewood Suites Appleton by IHG

Candlewood Suites Appleton by IHG
2.5 star property
6.5 km from Appleton Medical Center
8.8 out of 10, Excellent, (485)
"Clean rooms, stocked and easy access parking. "
United States
Boon Mee
The price is RM320
RM370 total
includes taxes & fees
30 Dec - 31 Dec
Candlewood Suites Appleton by IHG
Fridge, microwave, stovetop, dishwasher
MainStay Suites Appleton Airport - Fox River Mall Area

MainStay Suites Appleton Airport - Fox River Mall Area

MainStay Suites Appleton Airport - Fox River Mall Area
3.0 star property
6.2 km from Appleton Medical Center
8.6 out of 10, Excellent, (208)
"Friendly employees, great amenities, room had everything needed"
United States
Axel
The price is RM289
RM334 total
includes taxes & fees
11 Jan - 12 Jan 2026
MainStay Suites Appleton Airport - Fox River Mall Area
Down duvets, individually furnished, desk, iron/ironing board
Four Points by Sheraton Appleton

Four Points by Sheraton Appleton

Four Points by Sheraton Appleton
3.0 star property
6.3 km from Appleton Medical Center
8.6 out of 10, Excellent, (1000)
"Room was very clean, staff was really helpful. Great stay!"
United States
Calvert
The price is RM433
RM501 total
includes taxes & fees
25 Jan - 26 Jan 2026
Four Points by Sheraton Appleton
Interior
Wingate by Wyndham Appleton

Wingate by Wyndham Appleton

Wingate by Wyndham Appleton
2.5 star property
6.1 km from Appleton Medical Center
8.4 out of 10, Very good, (1003)
"Great room at a great price!"
United States
Jeffrey
The price is RM311
RM359 total
includes taxes & fees
19 Jan - 20 Jan 2026
Wingate by Wyndham Appleton
Indoor pool
Wyndham Garden Appleton

Wyndham Garden Appleton

Wyndham Garden Appleton
2.5 star property
6.2 km from Appleton Medical Center
8.4 out of 10, Very good, (1001)
"Yes great breakfast and clean rooms and friendly staff"
United States
Gregory
The price is RM434
RM501 total
includes taxes & fees
29 Dec - 30 Dec
Wyndham Garden Appleton
Front of property
GrandStay Hotel & Suites Kaukauna

GrandStay Hotel & Suites Kaukauna

GrandStay Hotel & Suites Kaukauna
2.0 star property
9.7 km from Appleton Medical Center
9.4 out of 10, Exceptional, (50)
"Clean room, gym does the job & staff was super nice"
United States
Ainsley
The price is RM361
RM417 total
includes taxes & fees
4 Jan - 5 Jan 2026
GrandStay Hotel & Suites Kaukauna
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Appleton Medical Center Hotel Reviews

Cobblestone Hotel & Suites-Little Chute

Cobblestone Hotel & Suites-Little Chute

10/10 Excellent
"Really nice room and the hot breakfast was a nice surprise, plus located in a good area. Great staff!"
Dwayne 3-night trip
Posted 5 days ago
Cobblestone Hotel & Suites-Little Chute

Hotels near other Appleton Medical Center attractions

Erb Park

4.1/5 (43 reviews)
After visiting Erb Park, make a plan to see the other sights and activities in Appleton. Attend a sporting event or visit the shops in this family-friendly area.
See properties

Super Bowl Family Entertainment Center

You can take time to visit Super Bowl Family Entertainment Center during your travels to Appleton. Visit the shops and top-notch restaurants in this family-friendly area.
See properties

Frequently asked questions

What's the area like around Appleton Medical Center?
Appleton Medical Center is located in a family-friendly area of Appleton that travellers like for its breweries and sporting events. If you're looking for a convenient place to stay, take a look at the 30 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Appleton Medical Center?
Hilton Appleton Paper Valley is one of the top choices for your stay based on our traveller data, and this hotel offers 3 restaurants and 2 bars. It's located 1.4 mi (2.2 km) from Appleton Medical Center. Other good options within 5 miles include AmericInn by Wyndham Appleton Downtown and CopperLeaf Boutique Hotel & Spa, BW Premier Collection.
How many hotels will I find close to Appleton Medical Center?
Expedia has 30 hotels and other accommodation options within a mile from Appleton Medical Center.
If I need to cancel the hotel reservation for my stay near Appleton Medical Center, will I receive a refund?
Yes, most hotel reservations are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then use the filter option "fully refundable" to view the best options available near Appleton Medical Center.
What can I see and do near Appleton Medical Center?
You'll want to browse the collections at Hearthstone Historic House Museum, History Museum at the Castle and Trout Museum of Art. You can wander around Appleton Memorial Park, Gordon Bubolz Nature Preserve or Erb Park if you want a dose of fresh air. Gardens of the Fox Cities, Building for Kids Children's Museum and Badger Sports Park are fun stops for the whole family while you're in town.