Theoxenia Caldera in Fira Santorini was an incredibly clean, with large rooms. We stayed in room #2, Monterra(?) . The terrace has amazing views of the sunset behind the volcanic island and the white rock. While we did not use it in early season, the outdoor pool with water jets provides for extra ordinary views. It's nestled above the shopping stores on the main walk way. Two amazing ice cream shops right at your desire's door step.
The rooms were spacious with a balcony. Our room balcony looked over the street and the amazing waters of the Santorini. However, we had limited views due to the buildings in front of us. If you are tall, you can see the water and the volcano - else get to the terrace.
The staff was extremely helpful, kind and attentive. We had an issue with the toilet flush not working well and they looked into it right away.
Getting to hotel from airport is a 30 Euro drop (pre-season) and a bus is available back to port or airport for about 2 Euro's. Either way, you have to walk about 3 city blocks to get to hotel from any transport option.
If you don't like going up the stairs for any number of reasons, this is not the place for you as it has about 14 odd steps to get from street level to lobby. No elevator that we could see.
Over all, a great experience. We would stay here again.